Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment
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چکیده
منابع مشابه
Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment
The diagnosis of early and aggressive types of cancer is important for providing effective cancer therapy. Cancer-induced fibrin clots exist only within lesions. Previously, we developed a monoclonal antibody (clone 102-10) that recognizes insoluble fibrin but not fibrinogen or soluble fibrin and confirmed that fibrin clots form continuously in various cancers. Here, we describe the development...
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darone withdrawal can lead to under-anticoagulation, and therefore to an increased risk of thrombosis. In conclusion, we describe the first case of genetic VKA resistance in a child who had the p.Asp36Tyr mutation combined with g. 1185G>A and g. 679A>G mutations in the 5′-flanking region. VKA resistance was partially masked initially by concomitant amiodarone therapy. Both warfarin–drug interac...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep23613